PP-167 The Relation between Digoxin and Appropriate Shocks in Patients with Ischemic Heart Failure and Implantable Cardioverter Defibrillator




Objective


Although digoxin improves heart failure symptoms, its potential proarrhythmic effects on ischemic myocardium has been debated. In this cross-sectional study, we investigated the relation between appropriate shocks in patients with ischemic heart failure (HF) and implantable cardioverter defibrillator (ICD).




Material-Method


In between January 2014 and August 2015, patients who were admitted to our hospital for routine ICD controls were evaluated according to the presence of appropriate ICD therapy.




Material-Method


In between January 2014 and August 2015, patients who were admitted to our hospital for routine ICD controls were evaluated according to the presence of appropriate ICD therapy.




Results


A total of 139 patients were included in the present study. Of these 35 patients (25.1%) experienced appropriate ICD shocks. In patients with ICD shocks, baseline left ventricular ejection fraction (LVEF) was significantly lower (p=0.009). When patients were compared according to the medications used, the number of the patients using aspirin and diuretic was significantly higher in the shock-received group whereas, statin usage was significantly lower in the shock-received group (p=0.030, p=0.046, p=0.044; respectively). Digoxin usage did not differ between the groups (p=0,388). In logistic regression analysis, aspirin usage and LVEF were found as independent predictors of ICD shocks (p=0.032 and p=0.045).

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Nov 27, 2016 | Posted by in CARDIOLOGY | Comments Off on PP-167 The Relation between Digoxin and Appropriate Shocks in Patients with Ischemic Heart Failure and Implantable Cardioverter Defibrillator

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