PP-149 Suppression of Refractory Electrical Storm by Microtubule Destabilization and Dechanneling Therapy in a Patient with Heart Failure with Reduced Left Ventricular Ejection Fraction and Implantable Cardioverter-Defibrillator:A Novel Therapeutic Approach




Aims


We prospectively investigated and followed up the impact of microtubule destabilization and dechanneling therapy on suppression of refractory electrical storm (ES) in a 63-year-old male patient with ischemic heart failure with reduced left ventricular ejection fraction (HFrEF),who had a history of previous coronary artery bypass grafting (CABG) and implantable cardioverter-defibrillator (ICD).




Methods


We have implemented 0.5mg a low-dose adjuvant colchicine once daily with a view to prevent ES of the patient in addition to conventional medication to ensure the microtubule destabilization and the pharmacological scar dechanneling because ES of the patient’s resistance for conventional pharmacological treatment and multiple antiarrhythmic interventions (ATP) delivered from ICD and due to the deterioration of the overall situation,




Methods


We have implemented 0.5mg a low-dose adjuvant colchicine once daily with a view to prevent ES of the patient in addition to conventional medication to ensure the microtubule destabilization and the pharmacological scar dechanneling because ES of the patient’s resistance for conventional pharmacological treatment and multiple antiarrhythmic interventions (ATP) delivered from ICD and due to the deterioration of the overall situation,

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Nov 27, 2016 | Posted by in CARDIOLOGY | Comments Off on PP-149 Suppression of Refractory Electrical Storm by Microtubule Destabilization and Dechanneling Therapy in a Patient with Heart Failure with Reduced Left Ventricular Ejection Fraction and Implantable Cardioverter-Defibrillator:A Novel Therapeutic Approach

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