Objective
>Echocardiographic mitral valve E point-septal separation (EPSS) has been found to be a useful hemodynamic index and simple measurement that reflects LV function. Prior studies have shown a high negative correlation between EPSS and left ventricular ejection fraction (EF). The Framingham Heart Study showed an apparently continuous relation between LVM and cardiovascular event rate in the general population. The aim of this study was to determine if there were a correlation between LVMI and EPSS at heart failure patients.
Methods
One hundred fourty four(144) patients(99 male, 45 female) who has heart failure were evaluated using echocardiography. Only frames with optimal visualization of interfaces and simultaneously showing septum, LV interventricular septum, and posterior wall were used for readings. LV mass was calculated using M-mode LV measurements by Penn and American Society of Echocardiography (ASE) conventions and cube function and volume correction formulas. LVM index(LVMİ) was calculated with normalization of left ventricular mass by height. The relative wall thickness(RWT=2*posterior wall thickness/LV end diastolic diameter) also was calculated. The EPSS was measured in millimeters (mm) as the minimal separation distance between the mitral valve anterior leaflet and the ventricular posterior septum in M-mod echocardiography. No subject had ventricular aneurysm, severe right ventricular volume overload or hypertrophic cardiomiyopathy. Patients who have atrial fibrillation and significant valve disease were excluded from the study. Statistical analysis was performed using SPSS Version 15. Probability values <0.05 were considered statistically significant in analyses.
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