PP-076 Global and Regional Longitudinal Strain of Left Ventricle Is Significantly Reduced in Echocardiography in Patients with Hypertrophic Cardiomyopathy




Background


Hypertrophic cardiomyopathy (HCM) is a myocardial disease characterized with myocardial disarray and abnormally increased left ventricular (LV) wall thickness. Either myocardial disarray or abnormally increased thickness of LV myocardium consequences with relaxation abnormalities of LV. However it was documented that LV had several components of relaxation motion. In this study we evaluated whether global and regional strain properties of patients with HCM changed.




Material Method


Thirty two patients with HCM and nineteen healthy subjects were enrolled to the study. Left ventricle regional (anterior, lateral, septal, inferior) and global longitudinal, radial, and circumferential strain velocities were measured. The data were compared among patients with HCM and control group. Correlation analysis of left ventricle echocardiographic parameters and strain velocities was performed study group.




Material Method


Thirty two patients with HCM and nineteen healthy subjects were enrolled to the study. Left ventricle regional (anterior, lateral, septal, inferior) and global longitudinal, radial, and circumferential strain velocities were measured. The data were compared among patients with HCM and control group. Correlation analysis of left ventricle echocardiographic parameters and strain velocities was performed study group.




Results


We found that LV longitudinal strain (-21.00±2.38 vs -11.03±2.02, p<0.001) was significantly reduced in patients with HCM. Additionally regional anterior, septal, and inferior, lateral longitudinal strain were significantly reduced in patients with HCM. Moreover regional inferior radial strain, regional anterior and septal circumferential strain were significantly reduced in patients with HCM. Correlation analysis revealed that increased thickness of interventricular septum is significantly correlated LV longitudinal strain, regional anterior longitudinal strain, regional septal longitudinal strain and regional inferior longitudinal strain (Figure 1).

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Nov 27, 2016 | Posted by in CARDIOLOGY | Comments Off on PP-076 Global and Regional Longitudinal Strain of Left Ventricle Is Significantly Reduced in Echocardiography in Patients with Hypertrophic Cardiomyopathy

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