Methods
This cross-sectional study included 38 male patients (aged 45 years and below) and 12 female patients (aged 55 years and below) admitted to the cardiology outpatient clinics or emergency room with complaint of acutely started chest pain or dyspnea who were indicated for ETT and MSCT to rule out presence of CAD. Subjects with positive family history for CAD, with moderate risk for developing CAD according to the Framingham risk scale and with negative or non-diagnostic ETT results were included in the study. LDL level of ≥160 mg/dl was defined as presence of hyperlipidemia. MSCT and ETT results were compared.
Methods
This cross-sectional study included 38 male patients (aged 45 years and below) and 12 female patients (aged 55 years and below) admitted to the cardiology outpatient clinics or emergency room with complaint of acutely started chest pain or dyspnea who were indicated for ETT and MSCT to rule out presence of CAD. Subjects with positive family history for CAD, with moderate risk for developing CAD according to the Framingham risk scale and with negative or non-diagnostic ETT results were included in the study. LDL level of ≥160 mg/dl was defined as presence of hyperlipidemia. MSCT and ETT results were compared.
Results
CAD was diagnosed in 15 out of 44 patients (34.0%). According to MSCT results, there were 15 subjects with LAD proximal, 7 with RCA proximal, 4 with LCx proximal, 3 with LAD mid-segment, 1 with RCA mid-segment, 1 with the first diagonal branch, 1 with the first obtuse marginalis branch, 1 with LCx distal and 1 with LMCA involvement of any degree. Of the patients diagnosed with CAD, seven (46.6%) had critical stenosis (≥50% luminal narrowing) and eight (53.4%) had non-critical stenosis (<50% luminal narrowing). Age, gender and body mass index (BMI) of the subjects with or without hyperlipidemia were similar. Nine patients with hyperlipidemia (40.9%) and six patients without hyperlipidemia (27.2%) had CAD (p>0.05). There was no statistically significant difference between the subjects with negative ETT (n=29) and with non-diagnostic ETT (n=15) in respect to age, gender and smoking status. The prevalence of DM (p<0.01) and HT (p<0.05) was significantly higher in patients with non-diagnostic ETT results. There was no statistically significant difference between the groups in terms of HDL, LDL levels, BMI, and the presence of multiple risk factors (>3 major cardiovascular risk factors). Nine patients with non-diagnostic ETT (60.0%) and six patients with negative ETT (20.6%) had CAD (p<0.01).
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