Aim
Mortality of patients from STEMI or NSTEMI mainly depends on the burden of thrombotic process and myocardial injury and consequently the irreversible loss of myocardial function. Platelet indices could present variation since they could be influenced by the highly active thrombotic process resulting high turnover and large myocardial tissue injury resulting with increased inflammatory activity. From this point of view we evaluated whether platelet indices variation in patients suffered death from STEMI and NSTEMI acute coronary syndrome (ACS) and in patients who survived from ACS.
Material-Method
We evaluated the platelet indices; platelet count, Mean platelet volume, and Platelet distribution width; from the CBC parameters among those patient suffered death from STEMI (n=22) and NSTEMI (n=28) acute coronary syndrome (ACS) and survived from ACS (n=29). Comparisons and subgroup analysis were performed by Kruskal Wallis test and Mann Whitney U test.
Material-Method
We evaluated the platelet indices; platelet count, Mean platelet volume, and Platelet distribution width; from the CBC parameters among those patient suffered death from STEMI (n=22) and NSTEMI (n=28) acute coronary syndrome (ACS) and survived from ACS (n=29). Comparisons and subgroup analysis were performed by Kruskal Wallis test and Mann Whitney U test.
Results
We observed that platelet count were significantly reduced in death from NSTEMI ACS group compared to other groups while MPV significantly elevated in NSTEMI ACS group compared to only survivor group (p=0.032) and PDW were significantly elevated both in NSTEMI (p=0.011) and STEMI (0.039) group compared to survivors from ACS (Table 1, Figure 1).