PP-039 Reduction of Eosinophil may Predict Mortality from NSTEMI Acute Coronary Syndromes




Aim


Recently it has been reported that eosinophil could be associated with the myocardial injury and the burden of thrombosis in acute coronary syndromes (ACS). In this pilot study we evaluated complete blood count parameters including eosinophil, basophil, and neutrophil, lymphocyte and their ratio among the patients suffered death from STEMI and NSTEMI ACS and also their survivors in which the mortality or survival could directly represent the severity of myocardial injury and thrombotic process.




Material-Method


We evaluated the CBC parameters among the patients who suffered death from STEMI ACS (n=22) and NSTEMI ACS (n=28) and the ones survived (n=29) from ACS. Comparison of data and subgroup analysis were performed by Kruskal Wallis and Mann Whitney test, respectively.




Material-Method


We evaluated the CBC parameters among the patients who suffered death from STEMI ACS (n=22) and NSTEMI ACS (n=28) and the ones survived (n=29) from ACS. Comparison of data and subgroup analysis were performed by Kruskal Wallis and Mann Whitney test, respectively.




Results


We observed that WBC, Neutrophil% and Lymphocyte% were significantly elevated in group of death from STEMI and NSTEMI compared to survivors from ACS. Eosinophil% was significantly reduced in NSTEMI and STEMI mortality group compared to survivors from ACS (Table 1, Figure 1). Also we found that eosinophil percentage ≤1.05 could predict the mortality from NSTEMI with a sensitivity and specificity of 57% and 94%, (AUC=0.803, CI 0.685-0.921, p<0.001).

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Nov 30, 2016 | Posted by in CARDIOLOGY | Comments Off on PP-039 Reduction of Eosinophil may Predict Mortality from NSTEMI Acute Coronary Syndromes

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