Objectives
Acute pulmonary embolism is a disorder caused by thrombotic occlusion of the pulmonary arteries. Despite advanced therapeutic options it is a lifethreatening condition. We aimed to investigate the changes of platelet indices including platelet count, mean platelet volume and platelet distribution width in patients with massive pulmonary embolism and to evaluate their diagnostic value.
Methods
The study group consisted of 90 patients with massive pulmonary embolism and 146 patients without pulmonary embolism as the control group admitted to emergeny department from 2012 to 2016. Exclusion criteria included acute coronary syndromes, hematological disorders, severe hepatic and renal diseases, chronic pulmonary hypertension, diabetes mellitus, hypothyroidism, chronic inflammatuar diseases, malignancy, pregnancy and anticoagulation therapy used. From the medical records of the patients we analyzed the differences in platelet count, mean platelet volume, platelet distribution width, d-dimer and other indicators retrospectively. Computed tomography of the thorax and echocardiography confirmed the diagnosis of massive pulmonary embolism when they admitted to the emergency department. Venous periphal blood samples for measurement were drawn on admission, before treatment and at the time of diagnosis.
Methods
The study group consisted of 90 patients with massive pulmonary embolism and 146 patients without pulmonary embolism as the control group admitted to emergeny department from 2012 to 2016. Exclusion criteria included acute coronary syndromes, hematological disorders, severe hepatic and renal diseases, chronic pulmonary hypertension, diabetes mellitus, hypothyroidism, chronic inflammatuar diseases, malignancy, pregnancy and anticoagulation therapy used. From the medical records of the patients we analyzed the differences in platelet count, mean platelet volume, platelet distribution width, d-dimer and other indicators retrospectively. Computed tomography of the thorax and echocardiography confirmed the diagnosis of massive pulmonary embolism when they admitted to the emergency department. Venous periphal blood samples for measurement were drawn on admission, before treatment and at the time of diagnosis.