PP-006 Value of Duke Treatmill Score in the Predicting Coronary Artery Disease Presence and Severity




Objectives


We aimed to investigate the role of duke treatmill score (DTS) in predicting the presence and extent of coronary artery disease (CAD) by using the SYNTAX score and also to determine the cut-off values of DTS for both presence and severity of CAD.




Methods


The study population consisted of 267 patients with chest pain who had undergone coronary angiography after treatmill stress test. First the patients were divided into two groups: CAD (+) and CAD(-). Then the patients with CAD were classified into two subgroups with low (0-22) and high (>22) SYNTAX score.




Results


The average values of DTS and SYNTAX scores in all of the patients were -6 ± 6 and 11 ± 11 respectively. While 31% of all patients with a SS of 0, 40% had low SS and 29% had high SS. DTS differed significantly between SS=0 and SS>0 groups (p <0.001). In the SS>0 group, DTS was detected to be -4 ± 3 and -13 ± 5 in the low and high SS groups respectively. High SS group had significantly higher values of DTS when compared to low SS group (p <0.001). A strong negative correlation was found between DTS and SS. (r = -0.72, p <0.001). Receiver operating characteristic (ROC) curve analysis was performed to establish cut-off values of the DTS for predicting SS>0 and high SS. In Roc analysis, the cut-off value of DTS between SS=0 and SS>0 groups was -3.7 [AUC=0.83 (0.77-0.88, p<0.001), sensitivity 74%,specificity 73% ], while it was -11.2[AUC=0.84(0.78-0.90,p0.001), sensitivity 81%,specificity 80% between low and high SYNTAX groups. A multivariate regression analysis was performed for the predictors of SYNTAX Score. In this analysis, diabetes, eGFR and DTS were an independent predictors of high SYNTAX Score (b: 0.109, p<.056, b: 0.133, P =.003 and b:0524, p<.001 respectively).

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Nov 30, 2016 | Posted by in CARDIOLOGY | Comments Off on PP-006 Value of Duke Treatmill Score in the Predicting Coronary Artery Disease Presence and Severity

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