Methods
The study population consisted of 267 patients with chest pain who had undergone coronary angiography after treatmill stress test. First the patients were divided into two groups: CAD (+) and CAD(-). Then the patients with CAD were classified into two subgroups with low (0-22) and high (>22) SYNTAX score.
Results
The average values of DTS and SYNTAX scores in all of the patients were -6 ± 6 and 11 ± 11 respectively. While 31% of all patients with a SS of 0, 40% had low SS and 29% had high SS. DTS differed significantly between SS=0 and SS>0 groups (p <0.001). In the SS>0 group, DTS was detected to be -4 ± 3 and -13 ± 5 in the low and high SS groups respectively. High SS group had significantly higher values of DTS when compared to low SS group (p <0.001). A strong negative correlation was found between DTS and SS. (r = -0.72, p <0.001). Receiver operating characteristic (ROC) curve analysis was performed to establish cut-off values of the DTS for predicting SS>0 and high SS. In Roc analysis, the cut-off value of DTS between SS=0 and SS>0 groups was -3.7 [AUC=0.83 (0.77-0.88, p<0.001), sensitivity 74%,specificity 73% ], while it was -11.2[AUC=0.84(0.78-0.90,p0.001), sensitivity 81%,specificity 80% between low and high SYNTAX groups. A multivariate regression analysis was performed for the predictors of SYNTAX Score. In this analysis, diabetes, eGFR and DTS were an independent predictors of high SYNTAX Score (b: 0.109, p<.056, b: 0.133, P =.003 and b:0524, p<.001 respectively).