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22. Balloons: Plain, Drug-Coated, and Cutting
Balloon Angioplasty
Arterial angioplasty was first reported by Dotter and Judkins in 1964 for the treatment of peripheral vascular lesions using rigid intravascular dilators [1]. Inflation of an angioplasty balloon in the artery causes dissection of the atherosclerotic plaque and adjacent intima. The medial and adventitial layers are also dilated. This controlled stretch injury increases the cross-sectional area of the vascular lumen. Over several weeks, the artery remodels via re-endothelialization of the intima [2, 3].
Types of Balloon Catheter
The two main types of balloon delivery catheters are over the wire (OTW) catheters and single operator exchange (SOE) catheters.
Both types of angioplasty balloon delivery catheters come in a variety of shaft lengths and outer diameter profiles. The shaft length is critical to determine whether the catheter is of adequate length to reach the target lesion. The shaft length also must be longer than the sheath or guiding catheter through which the balloon delivery catheter is being advanced. As an example, if a 90-cm destination sheath is placed, then a 75-cm working length balloon will not reach the lesion. The outer diameter profile will determine the minimum inner diameter of the sheath or guiding catheter through which the balloon can be advanced. In general, smaller-profile balloons are more likely to succeed in crossing extremely stenotic or occluded lesions. It is also important to note the recommended wire diameter. Balloon catheters often can be advanced over wires smaller than the recommended size, but not over wires that are larger. This can be helpful when using low-profile balloons over 0.014 wire for tibial lesions in which the same wire can be used for treating femoropopliteal lesions that usually go over an 0.035 wire. Note that there will be bleeding from the manifold because the wire is smaller in diameter.
Balloon delivery catheter specifications are listed on the packaging and should be noted prior to passing the device to the sterile field, to avoid waste. It is always a good idea to ensure sheath and wire compatibility before opening a balloon.
Angioplasty Technique: General Principles
Crossing the lesion: After obtaining vascular access, arteriography is performed to identify the lesion. The target vessel stenosis is crossed with a wire and support catheter. Once the lesion is crossed, the wire is withdrawn and contrast is injected into the crossing catheter to confirm its location in the true lumen. The wire is then re-advanced and the support catheter is exchanged for the balloon delivery catheter.
Balloon sizing