Methods
Our study included 94 patients with SCAD (mean age 59 ± 9,67 years). All patients underwent elective PCI with DES implantation during dual antiplatelet therapy (aspirin and clopidogrel). Platelet function was assessed by light transmission aggregometry with 5μmol/L ADP (LTA-ADP), and also by the method VerifyNow® before PCI. All patients underwent genotyping to detect CYP2C19polymorphism. HOPR was defined as maximal platelet aggregation by 5μmol/L ADP ≥ 50% by LTA and PRU value≥ 208 according to VerifyNow®.
Methods
Our study included 94 patients with SCAD (mean age 59 ± 9,67 years). All patients underwent elective PCI with DES implantation during dual antiplatelet therapy (aspirin and clopidogrel). Platelet function was assessed by light transmission aggregometry with 5μmol/L ADP (LTA-ADP), and also by the method VerifyNow® before PCI. All patients underwent genotyping to detect CYP2C19polymorphism. HOPR was defined as maximal platelet aggregation by 5μmol/L ADP ≥ 50% by LTA and PRU value≥ 208 according to VerifyNow®.
Stay updated, free articles. Join our Telegram channel
Full access? Get Clinical Tree
