Objective
Silent cerebral ischemia (SCI) is an embolic origin cerebrovascular lesion due to embolic vascular occlusion incidentally diagnosed. Coronary angiography (CAG) is established as the gold standard for the assessment of coronary artery disease. However there are minor and major complications related to the procedure. Retrospective data analysis revealed that 0.11% to 0.38% of patients undergoing CAG experienced clinically evident cerebral infarction whereas the incidence of SCI was 13% to 22%. To date, limited data were available regarding the occurrence and predictors of SCI after CAG. In our study we aim to evaluate the incidence and predictors of SCI after CAG.
Method
One hundred one stable coronary artery disease patients without atrial fibrillation and history of serebrovascular disorders underwent coronary anjiography and intervention were included in this study. Percutaneous coronary interventions were performed for selected patients. Cerebral magnetic resonance imaging and diffusion weighted magnetic resonance imaging (DW-MRI) were performed within 24 hours after diagnostic coronary anjiography. Silent cerebral infarction (SCI) was diagnosed with the presence of focal bright high signal intensity on DW-MRI. Patients were divided into diagnostic coronary anjiography and intervention group. Each groups were assessed with presence or absence of SCI. The laboratory findings, clinical and angiographic characteristics were analyzed and compared between patients with and without SCI on DW-MRI.
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