Aim
Determining left ventricle (LV) ejection fraction (EF) is clinically important for the diagnosis of congestive heart failure and also its follow up. Determination of LVEF by using Simpson method is the most accurate way of it. However it may be sometimes determinative due to either anatomical variation of LV or echocardiographers’ experiences on Simpson method.
Material-Method
Totally, 42 patients with signs and symptoms of CHF and 40 asymptomatic subjects as control group were enrolled to the study. We measured and compared the aortic flow parameters; aortic flow acceleration and deceleration time, aortic max velocity and max and mean gradient, and also aortic velocity time integral patients with congestive heart failure and control group. We evaluated the relationship of aortic flow acceleration/deceleration time ratio by regression analysis and analyzed its role on predicting the reduced LVEF in CHF.
Material-Method
Totally, 42 patients with signs and symptoms of CHF and 40 asymptomatic subjects as control group were enrolled to the study. We measured and compared the aortic flow parameters; aortic flow acceleration and deceleration time, aortic max velocity and max and mean gradient, and also aortic velocity time integral patients with congestive heart failure and control group. We evaluated the relationship of aortic flow acceleration/deceleration time ratio by regression analysis and analyzed its role on predicting the reduced LVEF in CHF.
Results
We found that AoAccT (65.8±12.2 vs 80.3±17.5, p<0.001) was significantly prolonged whereas AoDecT (244.1±27.2 vs 219.5±41.6, p=0.003) was significantly shortened in patients with CHF compared to control group. LVEF MMod and Simpson (64,58±3,34 vs 37,36±8,28, p<0.001) were also reduced in patients with CHF. We observed that ratio of aortic flow acc/dec time (0.27±0.06 vs 0.39±0.14, p<0.001) was significantly increased in patients with CHF. Additionally we found that AoAcc/DecTime ratio was significantly correlated with LVEF Simpson (R=0.575, R2=0.331, AdjR2=0.323, β=-575, p<0.001). Also the AFlow Acc/Dec Ratio >0.30 could predict the LVEF <50% with a sensitivity and specificity of 66% and 75%, respectively (AUC 0.763, CI 0.660-0.865, p<0.001). Moreover AFlow Acc/Dec Ratio >0.43 could predict LVEF <35% with a sensitivity and specificity of 60% and 95%, respectively (AUC 0.775, CI 0.594-0.956, p=0.001). Heart rates which could influence the aortic flow time properties were not different among groups.
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