Methods
The study enrolled 31 PCOS patients and 32 healthy volunteers as a control group. The participants’ ages ranged between 18 and 40 years. PCOS was diagnosed according to the Rotterdam criteria. LV strain (S) and strain rate (SR) were evaluated using apical two- (2C), three- (3C), and four-chamber (4C) imaging. Global S and SR were calculated by averaging the three apical views.
Methods
The study enrolled 31 PCOS patients and 32 healthy volunteers as a control group. The participants’ ages ranged between 18 and 40 years. PCOS was diagnosed according to the Rotterdam criteria. LV strain (S) and strain rate (SR) were evaluated using apical two- (2C), three- (3C), and four-chamber (4C) imaging. Global S and SR were calculated by averaging the three apical views.
Results
The waist-to-hip ratio, HOMA-IR (homeostasis model assessment-insulin resistance), and fasting insulin and triglyceride levels were higher in the PCOS group than in the controls (P = 0.001, P = 0.001, P = 0.001, and P = 0.005, respectively). In the PCOS group, the mitral A wave, deceleration time (DT), and isovolumetric relaxation time (IVRT) were significantly higher than in the controls (all P < 0.05). The LV global longitudinal strain (LV-GLS) and global longitudinal strain rate (GLSRS) were significantly lower in the PCOS patient group (both P = 0.001). There were strong negative correlations between LV-GLS and both fasting insulin (r = –0.64) and DT (r = –0.62) (both P < 0.05).
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