Background
Vasovagal syncope (VVS) is widely believed to be more common in women than men. Although, VVS is supposed to be modulated by increased sympathetic tone following an orthostatic maneuver, the underlying mechanism, which explains this female predisposition is not fully elucidated. The aim of this study is to evaluate the gender differences with regard to time-domain HRV parameters in patients with vasovagal syncope.
Material-mehod
Patients with VVS referred to our Cardiology Clinic have undergone 24-hour holter monitoring for heart rate variability (HRV) and time-domain HRV analysis. Blood samples for CBC analysis were obtained. Patients were divided into 2 groups according to sex. Group 1 was consisted of male patients and group 2 was consisted of female patients. HRV analyses of the subjects were compared.
Material-mehod
Patients with VVS referred to our Cardiology Clinic have undergone 24-hour holter monitoring for heart rate variability (HRV) and time-domain HRV analysis. Blood samples for CBC analysis were obtained. Patients were divided into 2 groups according to sex. Group 1 was consisted of male patients and group 2 was consisted of female patients. HRV analyses of the subjects were compared.
Results
Forty-two male patients and 22 female patients were enrolled to this study. We observed that SDNN, SDANN and SDNN index were significantly lower in female patients with VVS (p < 0.05 for all). Correlation analysis showed that age, sex, mean heart rate and hemoglobin were significantly correlated with above time-domain HRV parameters (p < 0.05 for all).