OP-153 The Effects of Steroids Used for the Treatment of Childhood Asthma on Aortic Stiffness




Objective


The present study aimed to investigate the effects of steroid treatment in patients with newly diagnosed childhood asthma on aortic stiffness and to determine how such effects contribute to cardiovascular risk.




Methods


The study was performed in 45 pediatric patients diagnosed with bronchial asthma (BA). All patients were administered b2 agonist-salbutamol for five days, followed by one month of montelukast and three months of inhaled steroid- budesonide or fluticasone-furoate treatment. Pre- and post-treatment conventional transthoracic echocardiographic imaging was performed. Aortic elasticity parameters were considered to be the markers of aortic functions. For all patients, aortic systolic (AS) and diastolic (AD) indexes were calculated by dividing the systolic and diastolic aorta diameters by body mass index (BMI). Aortic elasticity parameters were calculated using these indexes. Pre- and post-treatment parameters were compared.




Methods


The study was performed in 45 pediatric patients diagnosed with bronchial asthma (BA). All patients were administered b2 agonist-salbutamol for five days, followed by one month of montelukast and three months of inhaled steroid- budesonide or fluticasone-furoate treatment. Pre- and post-treatment conventional transthoracic echocardiographic imaging was performed. Aortic elasticity parameters were considered to be the markers of aortic functions. For all patients, aortic systolic (AS) and diastolic (AD) indexes were calculated by dividing the systolic and diastolic aorta diameters by body mass index (BMI). Aortic elasticity parameters were calculated using these indexes. Pre- and post-treatment parameters were compared.

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Nov 30, 2016 | Posted by in CARDIOLOGY | Comments Off on OP-153 The Effects of Steroids Used for the Treatment of Childhood Asthma on Aortic Stiffness

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