Aim
Galectin is a novel serum biomarker of congestive heart failure and closely associated with myocardial fibrosis. Left atrial diameter and volumes could easily be imaged by echocardiography and may indirectly inform about the diastolic filling pressure of left ventricle and also presence of congestive heart failure (CHF). We evaluated the relationship of between Left atrial diameter (LAD), 2- and 4-chamber volumes and Galectin 3 and also their predictive role in diagnosis of CHF.
Material-Method
Totally, 42 patients with signs and symptoms of CHF and 40 asymptomatic subjects as control group were enrolled to the study. Left atrial diameter, 2- (LaVol2c) and 4- (LaVol4c) chamber volumes were calculated by echocardiographic examination. Serum levels of Galectin 3 were measured from the venous blood sample obtained at 12 hour fasting state. Regression analysis of LAD, LaVol2c, and LaVol4c and Galectin 3 was performed and predictive role of those parameters in diagnosis of CHF was evaluated by ROC curve analysis.
Material-Method
Totally, 42 patients with signs and symptoms of CHF and 40 asymptomatic subjects as control group were enrolled to the study. Left atrial diameter, 2- (LaVol2c) and 4- (LaVol4c) chamber volumes were calculated by echocardiographic examination. Serum levels of Galectin 3 were measured from the venous blood sample obtained at 12 hour fasting state. Regression analysis of LAD, LaVol2c, and LaVol4c and Galectin 3 was performed and predictive role of those parameters in diagnosis of CHF was evaluated by ROC curve analysis.
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