OP-136 Relationship Between Serum Anti-M2- muscarinic Receptor Levels and Atrial Electromechanical Delay in Patients Diagnosed with Paroxysmal Atrial Fibrillation




Objectives


Animal studies have demonstrated that rabbits immunized against M2- muscarinic receptors (M2- R) had longer intra-atrial activation times and shorter atrial effective refractory periods. Atrial electromechanical delay (AEMD) determined with echocardiography, allows evaluating atrial electrical remodeling, which has been shown to be related with initiation and maintenance of atrial fibrillation (AF). We aimed to determine whether serum anti-M2-R levels correlated with AEMD in paroxysmal AF patients.




Methods


35 paroxysmal AF patients with preserved left ventricular function were included in the study. Serum anti-M2-R levels were measured with ELISA. AEMD measurements were obtained from transthoracic echocardiography.




Methods


35 paroxysmal AF patients with preserved left ventricular function were included in the study. Serum anti-M2-R levels were measured with ELISA. AEMD measurements were obtained from transthoracic echocardiography.

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Nov 30, 2016 | Posted by in CARDIOLOGY | Comments Off on OP-136 Relationship Between Serum Anti-M2- muscarinic Receptor Levels and Atrial Electromechanical Delay in Patients Diagnosed with Paroxysmal Atrial Fibrillation

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