Aim
Although medical and interventional therapeutic options had provided particular improvement in the management of patients with acute coronary syndrome (ACS). Various parameters which were related with the myocardial damage or systemic inflammatory response had been defined as the criteria for the poor prognosis. Recently eosinophil, basophil had been reported as having a potential role within the interaction of thrombotic process, systemic inflammatory response and tissue damage. We evaluated the whether those parameters could have been utilized as a predictor for the worst prognosis of ACS, mortality.
Results
We observed that WBC, MPV, and PDW were significantly elevated and basophil tended to be slightly elevated (p=0.064) while eosinophil% was significantly reduced in mortality group (Table 1, Figure 1). Also we found that eosinophil percentage ≤1.45 could predict the mortality with sensitivity and specificity of 68% and 76%, (AUC=0.776, CI 0.672-0.879, p<0.001). Additionally WBC ≥11.7×103 could predict the mortality with sensitivity and specificity of 70% and 76%, (AUC=0.804, CI 0.709-0.899, p<0.001).