OP-035 Effect of Plasminogen Activator Inhibitor-1 and Factor XIII Gene Polymorphism on Admission Repolarization Parameters in ST-segment Elevation Myocardial Infarction




Aim


It has been known that ventricular repolarization plays an important role in ventricular arrhytmia. The aim of this study was to evaluate whether the plasminogen activator inhibitör 1 (PAI-1) and factor XIII gene polymorphism influence repolarization parameters in ST segment elevation myocardial infarction (STEMI). However, their relationship with repolarization parameters is known.




Study Design


We studied 108 patients (87 male and 21 female) with diagnosis of STEMI. For each patient, 12-lead electrocardiogram (ECG) with a paper speed of 50 mm/s was recorded on admission. QT interval, QT dipersion and the peak and end of T wave ( Tpe) interval were manually calculated. The Tpe/QT was calculated Tpe interval divided by the QT interval in the V5 lead.Blood samples were obtained from all patients for genetic analysis before reperfusion therapy.




Study Design


We studied 108 patients (87 male and 21 female) with diagnosis of STEMI. For each patient, 12-lead electrocardiogram (ECG) with a paper speed of 50 mm/s was recorded on admission. QT interval, QT dipersion and the peak and end of T wave ( Tpe) interval were manually calculated. The Tpe/QT was calculated Tpe interval divided by the QT interval in the V5 lead.Blood samples were obtained from all patients for genetic analysis before reperfusion therapy.

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Nov 30, 2016 | Posted by in CARDIOLOGY | Comments Off on OP-035 Effect of Plasminogen Activator Inhibitor-1 and Factor XIII Gene Polymorphism on Admission Repolarization Parameters in ST-segment Elevation Myocardial Infarction

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