Background
Impaired aortic elasticity (stiffness) is shown to be associated with cardiovascular morbidity and mortality in essential hypertension. Previous studies showed that activated monocytes and low HDL-cholesterol might have a role in arterial stiffness in hypertension. Recently, monocyte count-to-HDL cholesterol ratio (MHR) is found as a candidate marker of inflammation and oxidative stress. Therefore, we aimed to assess the association of MHR with aortic elastic properties in hypertensive patients.
Methods
A total of 114 newly-diagnosed and untreated patients with essential hypertension and 71 healthy control subjects were enrolled consecutively. Aortic stiffness (β) index, aortic strain and aortic distensibility (AoD) were measured with formulas by using transthoracic echocardiography and office blood pressure obtained by sphygmomanometer data. Study population was also categorized as median MHR <18.3 and ≥18.3.
Methods
A total of 114 newly-diagnosed and untreated patients with essential hypertension and 71 healthy control subjects were enrolled consecutively. Aortic stiffness (β) index, aortic strain and aortic distensibility (AoD) were measured with formulas by using transthoracic echocardiography and office blood pressure obtained by sphygmomanometer data. Study population was also categorized as median MHR <18.3 and ≥18.3.
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