In recent years, much attention is paid to the study of dispersions of (QTd) QT interval values in patients with arterial hypertension (AH) – the marker of repolarization inhomogeneity and the predictor of ventricular arrhythmias (VA).

Purpose of study: assessment of the relationship of left ventricular myocardial mass index (LVMI) and its relationship with ventricular repolarization indicators.

The study included 65 patients with arterial hypertension aged from 32 to 68 years (45 men and 20 women). According to the results of daily monitoring of ECG, QTc and QTd were determined. By the results of echocardiography, LVMI and type of LV hypertrophy (LVH) were assessed.

All patients were divided into 2 groups: LVMI in the first group (n=42) amounted to 92,4±1,96 g/m ² , in second group (n=23), it was 116,3±2,8 g/m ² (p<0,001).

The maximum elongation of QTd and QTc was observed in patients of Group 2, which was significantly lower by 17,7% and 15,6% respectively (p < 0.05) compared to the same indicators of the patients of Group 1. In patients with concentric LVH: QTd amounted to 74,1±3,3 msec and QTc – 421,6±2,9 msec; in those eccentric LVH: QTd – 61,08±3,12ms, QTc – 407,3±3,45ms. In eccentric LVH with ejection fraction less than 50%, QTd and QTc duration increased by 15,2% and 19,3% respectively, in concentric LVH, QTd increased by 21,8% and QTc by 29,3% (p<0,05). Correlation was disclosed between the frequency of VA and the increase in QTc and QTd (r=0,34; p < 0,05). Increase of QTd> 70 ms enhances VA with high gradations.

Thus, the change of integral indicators is associated with LVMI and concentric LVH, and eccentric LVH is associated with low values of EF. Increase in integral indicators is associated with the onset of VA with high gradations.