Objective
Sympathetic overactivity plays an important role on the development of resistant hypertension (RH). However, the effect of sympathetic predominance on left ventricular hypertrophy (LVH) in RH is not very clear. In our study, we aimed to evaluate the association between sympathetic overactivity and LVH in RH.
Methods
142 RH patients were enrolled in this study. Transthoracic echocardiography was performed on each case and LVH parameters (Interventricular septum and posterior wall thickness, left ventricular mass and left ventricular mass index) were assessed. 75 had echocardiographic evidence of LVH (RH / LVH (+)) while the other 67 patients did not (RH / LVH (-)). Mean heart rate and time domain heart rate variability (HRV) values (Standard deviation of NN intervals (SDNN), standard deviation of all five minute NN intervals (SDANN), Triangular index), which reflect sympathetic overactivity, were obtained from 24 hour ECG recordings. Mean heart rate and HRV values were compared between the two groups.
Methods
142 RH patients were enrolled in this study. Transthoracic echocardiography was performed on each case and LVH parameters (Interventricular septum and posterior wall thickness, left ventricular mass and left ventricular mass index) were assessed. 75 had echocardiographic evidence of LVH (RH / LVH (+)) while the other 67 patients did not (RH / LVH (-)). Mean heart rate and time domain heart rate variability (HRV) values (Standard deviation of NN intervals (SDNN), standard deviation of all five minute NN intervals (SDANN), Triangular index), which reflect sympathetic overactivity, were obtained from 24 hour ECG recordings. Mean heart rate and HRV values were compared between the two groups.
Stay updated, free articles. Join our Telegram channel
Full access? Get Clinical Tree
