Background
Left atrial (LA) size is considered as a marker of adverse outcome among patients with heart failure. Moreover prior studies evaluated LA size or volume is a predictor of poor prognosis in general population and in patients with coronary artery disease and preserved left ventricular function.
Methods
We enrolled 97 patients with coronary artery disease at mean age of 61±10. Most of patients (68%) had a NYHA class 0-II. The mean left ventricular ejection fraction (LVEF) was 50±13%; 20% of patients had LVEF ≤ 35%. Most of the patients underwent revascularization procedures in early follow-up period or previously: 47% were observed after coronary artery bypass grafting and 46% – after angioplasty with stenting. Standard ECHO and Holter ECG investigation were accomplished in all patients. We calculated: microvolt T-wave alternans; signal-averaged electrocardiography (SAECG) with calculation of filtered QRS duration and late ventricular potentials (LVP); mean corrected QT-interval duration and its circadian dynamics, heart rate turbulence (HRT), and heart rate variability (HRV). Laboratory tests included: serum creatinine, brain natriuretic peptide (BNP), NT-proBNP, C-reactive protein and troponine T levels.
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