Aortic Aneurysm

Impact of Aortic Grafts on Arterial Pressure: A Computational Fluid Dynamics Study

Vardoulis O, Coppens E, Martin B, et al (Ecole Polytechnique Fédérale de Lausanne, Switzerland; Katholieke Universiteit Leuven, Belgium; et al) Eur J Vasc Endovasc Surg 42:704–710, 2011^§

Abstract

Objective

Vascular prostheses currently used in vascular surgery do not have the same mechanical properties as human arteries. This computational study analyses the mechanisms by which grafts, placed in the ascending aorta (proximal) and descending aorta (distal), affect arterial blood pressure.

Methods

A one-dimensional cardiovascular model was developed and adapted to include the graft geometry with in vitro measured mechanical properties. Pressure at the aortic root and haemodynamic parameters were computed and compared for a control, proximal and distal graft case.

Results

In comparison to the control case, the proximal graft increased characteristic impedance by 58% versus only 1% change for the distal graft. The proximal and distal graft increased pulse pressure by 21% and 10%, respectively.

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