MR Technical Overviews


Objects/devices

Safety

Prosthetic heart valve or annuloplasty ring

Not considered contraindication

Implanted cardiac pacemaker

Generally not safe (except MR-compatible new ICDs)

Cardiac closure and occluder devices

MR safe

Implanted cardioverter-defibrillator (ICD)

Generally not safe (except MR-compatible new ICDs)

Loop recorder (event monitor)

MR conditional

Inferior vena cava filters

MR safe (most), MR conditional (few)

Hemodynamic support devices (LVAD, IABP, and so on)

Contraindication to MR

Aortic stent graft

MR safe except “Zenith AAA endovascular graft”

Sternal suture wire after surgery

MR safe

Coronary stents and peripheral stents

MR safe (most), MR conditional (a few stents)


LVAD left ventricular assist device, IABP intra-aortic balloon pump, AAA abdominal aortic aneurysm





22.1.3 Cardiac Gating


The most effective form of cardiac gating is ECG gating which requires a high-amplitude QRS complex. In case of inadequate QRS complex, we can use the peripheral pulse from fingertip pulse monitors. An arrhythmia may lead to inappropriate triggering and image blurring or artifacts. An arrhythmia rejection technique is useful but prolongs the acquisition time.



  • A prospective ECG gating (Fig. 22.1a)

    A311690_1_En_22_Fig1_HTML.jpg


    Fig. 22.1
    Methods of ECG gating. (a) Prospective ECG gating: we obtain signal data after the determined time from the R wave on ECG. Acquisition time is fixed regardless of the R-R interval. If there is a premature heartbeat, scanning ignores the irregular beat which causes image blurring. (b) Retrospective ECG gating: we obtain signal data throughout the entire R-R interval which will be filled with the allotted k-spaces. Acquisition time is variable according to the heart rate




    • Provides better temporal resolution images, but results in longer acquisition time


    • Is not sampled at the end of the cardiac cycle


    • Can be effective in evaluating cardiac anatomy or tumor


  • A retrospective ECG gating (Fig. 22.1b)



    • Can cause image blurring due to combining data from different cardiac cycles


    • Obtains imaging data from the whole cardiac cycle


    • Is less sensitive to arrhythmias


    • Is excellent in cine imaging for assessing regional and global wall motion


22.1.4 Respiratory Fixing


When the images are blurred and signal-to-noise ratio (SNR) is too weak due to the respiratory motion, increasing the number of image acquisitions helps to improve SNR and reduce respiratory motion artifacts [2]. There are different kinds of respiratory fixing methods used in the clinical settings.



  • Breath-holding by the patient



    • Is the most commonly used during image acquisition



      • In standard MR sequences


    • May be limited in acquisition time


    • Is less available in the elderly or severely ill patients


  • Respiratory gating (Fig. 22.2)

    A311690_1_En_22_Fig2_HTML.jpg


    Fig. 22.2
    Respiratory gating with navigator echo on the right diaphragm. Scanning is performed when the signal from the right diaphragm is positioned within the acquisition window. Image is good when a gating window is below 5 mm. Exp expiration phase, Insp inspiration phase, and Rt Diaph right diaphragm




    • Monitors the patients’ diaphragmatic motion


    • Obtains the images during the end-expiratory phase



      • With a specified gating window which is acceptable if < 5 mm


    • May be effective in patient with little cooperation


    • Can lead to overall extension of scan time


  • Free breathing mode


22.1.5 Contrast Enhancement


The bolus injection of contrast medium is helpful to increase the signal of the blood or the targeted tissue. 3D MRA study is useful in the evaluation of blood vessels. The early phase of enhancement in the targeted tissue is related to the vascularity of the tissue and also reflects the fractional blood volume of the tissue and the extravascular microcirculation of the contrast medium. The inflammation of the targeted tissue or the higher vascularity of the tumors may represent prominent early enhancement. Differential distribution of contrast medium in early dynamic phases is helpful to differentiate between the normal myocardium and the pathologic myocardium in ischemic conditions.

The late phase of enhancement in the targeted tissue can be used to evaluate the abnormal stasis of the contrast medium which is useful to evaluate the areas of fibrosis. Stasis of contrast medium in the myocardium is made more prominent on the images by using the inversion recovery pulse which suppresses the normal myocardial signal.



  • Injection of contrast media



    • Is favorable of bolus injection (with 4–5 mL/s for 2–4 s)


    • Follows by injection of a bolus of normal saline



      • To flush the remaining contrast agent out of the injection routes


  • Contrast media enhancement



    • Increases SNR for MR angiography


    • Enables to obtain sequential images of different structures



      • Such as artery or vein


    • Improves CNR for tissue characterization


    • Can be useful in obtaining multiple data sets of the targeted images



      • For the dynamic perfusion study


    • Can be utilized in the evaluation of the tumor or inflammation



      • Using the early contrast pooling images


    • Is helpful in the evaluation of the infarct myocardium



      • Using the delayed contrast pooling images


22.1.6 Basic Views of the Heart (Fig. 22.3)




A311690_1_En_22_Fig3a_HTML.jpgA311690_1_En_22_Fig3b_HTML.jpg


Fig. 22.3
Basic views of the heart. (a) Short-axis view, (b) four-chamber view, (c) three-chamber view, (d) two-chamber view, (e) RV outflow tract view, (f) aortic valve view, and (g) aortic arch (candy-cane) view

The heart is positioned in the thoracic cage with a little oblique direction to the standard view of the thorax. Therefore, cardiac MR images are generally obtained along the long and short axes of the heart rather than those of the thorax. The long axis of the heart is the line from the cardiac base to the apex, and the short axis is the line perpendicular to the long axis of the heart. Although we can obtain all cardiac views through the freely positioned acquisition windows in any orientation, we usually obtain the dedicated views similar to echocardiography to allow assessment of cardiac chamber morphology or function and to communicate effectively among the clinicians.



  • Two-chamber view



    • Can be obtained when the imaging plane passes through the center line of the mitral valve to the cardiac apex


  • Short-axis view



    • Can be obtained perpendicular to the long axis of the heart from two-chamber or four-chamber views


  • Four-chamber view



    • Can be obtained when the imaging plane passes through the center of the left ventricle through the inferior septum of the short-axis view of the heart


  • Three-chamber view



    • Can be obtained when the imaging plane passes through the center of the left ventricle and the aortic valve from the basal short-axis view of the heart


  • RVOT view with pulmonary bifurcation



    • Can be obtained when the imaging plane passes through the center of the right ventricle and the pulmonic valve from the basal short-axis view of the heart


  • Aorta arch (candy-cane) view



    • Can be obtained when the imaging plane passes through the center of the ascending and descending aorta from the axial view of the thorax


22.1.7 Preparation Pulse


MR signal intensity in many situations is too weak to provide an appropriate information from the targeted images. The preparation pulse plays a role to create a preexisting magnetization prior to the application of RF pulses destined for data readout. It was usually applied before the spin echo or gradient echo pulse sequences were performed. Major roles are enhancing tissue contrast and suppressing signal intensity from the targeted tissues. Preparation pulse may prolong the acquisition time.



  • Inversion pulse (Fig. 22.4)

    A311690_1_En_22_Fig4_HTML.jpg


    Fig. 22.4
    The role of inversion pulse. Inversion pulse uses 180° pulse to reverse longitudinal magnetization. Inversion pulse according to the inversion time can suppress the targeted tissues such as fat, water, myocardium, or blood




    • Is more effective for T1 weighting in the targeted tissue


    • Can generate a variety of image contrasts between tissues


    • Can be used before spin echo or gradient echo


    • Uses 180° pulse to reverse longitudinal magnetization


    • Can be used in suppressing the targeted tissues as follows:

      1.

      Double inversion pulses for black blood technique

       

      2.

      Triple inversion pulses for myocardial edema



      • With fat saturation technique

       

      3.

      Single inversion pulse for myocardium suppression



      • Used in viability imaging studies

       


  • T2 preparation pulse



    • Is more effective for T2 weighting in the targeted tissue


    • Is commonly used in T2 mapping for edema detection


    • Uses 90° RF pulse followed by a series of 180° RF pulse, then a −90° RF tip-up


    • Can be used in strengthening T2 weighting in the targeted tissues as follows:

      1.

      T2 mapping for edema detection [3]

       

      2.

      Myocardial signal (short T2) suppression



      • For coronary artery imaging [4]

       

      3.

      Black blood late Gd-enhancement study



      • For myocardial infarct imaging [5]

       



22.2 T1- and T2-Weighted Imaging


MR signal intensities usually depend on the repetition time (TR) and the echo time (TE). The repetition time is the time between consecutive excitations, and the echo time is the time between the excitation and the detection of the signal which are applied for the spin echo or gradient echo. We need to select an appropriate TR or TE to characterize the tissue components.


22.2.1 T1-Weighted Image






  • The contrast depends on the various T1 time constants of the different tissue types.


  • Used to visualize anatomy and differentiate fat from the surrounding tissues.


  • TE is short and TR is usually equal to one R-R interval for spin echo sequence.


  • Shows higher signal from fat tissue and lower signal from water.


  • Is very useful for comparison of pre- and post-contrast images.


22.2.2 T2-Weighted Image




Jul 13, 2016 | Posted by in CARDIOLOGY | Comments Off on MR Technical Overviews

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