In vitro assessment of physiological impact of recipient artery intervention on the contralateral donor artery




Abstract


Background


Donor artery fractional flow reserve (FFR) often improves after treatment of recipient artery stenosis, but the physiological mechanism underlying this phenomenon has not been elucidated. This study aimed to assess two novel equations that explain the donor–recipient artery interaction.


Method


Eq. (A) predicts the donor artery FFR after complete release of recipient artery stenosis, while Eq. (B) predicts the donor artery FFR after partial release of recipient artery stenosis. Eq. (B) is a general form of Eq. (A) .



<SPAN role=presentation tabIndex=0 id=MathJax-Element-1-Frame class=MathJax style="POSITION: relative" data-mathml='FFR′1−pred=FFR1−CFI1FFR2−CFI2−CFI1CFI21−FFR11−FFR2+CFI11−FFR11−CFI2/1−CFI1FFR2−CFI2′>FFR1pred=((FFR1CFI1)(FFR2CFI2)CFI1CFI2(1FFR1)(1FFR2)+CFI1(1FFR1)(1CFI2))/((1CFI1)(FFR2CFI2))FFR′1−pred=FFR1−CFI1FFR2−CFI2−CFI1CFI21−FFR11−FFR2+CFI11−FFR11−CFI2/1−CFI1FFR2−CFI2
F F R ′ 1 − pred = F F R 1 − C F I 1 F F R 2 − C F I 2 − C F I 1 C F I 2 1 − F F R 1 1 − F F R 2 + C F I 1 1 − F F R 1 1 − C F I 2 / 1 − C F I 1 F F R 2 − C F I 2

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Nov 14, 2017 | Posted by in CARDIOLOGY | Comments Off on In vitro assessment of physiological impact of recipient artery intervention on the contralateral donor artery

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