P (patients)
I (intervention)
C (comparator group)
O (outcomes measured)
Patients with Chronic Type B dissection
Endovascular treatment
Medical management (for uncomplicated type B dissection)
Open surgical repair (complicated type B dissection)
30 day mortality, early CVA and spinal cord ischemia (SCI), long-term survival, aortic event-free survival and rate of aortic re-interventions.
Table 2.2
Results for TEVAR in chronic complicated Type B aortic dissection
Author, year (ref.#) |
n |
30 day mortality N (%) |
Early CVA N (%) |
Early SCI N (%) |
Mean f/up (m) |
Survival (%) |
Aortic event freedom rate | |
---|---|---|---|---|---|---|---|---|
Aorta related death, reintervention, expansion free (%) |
Aorta related death free (%) | |||||||
Prospective nonrandomized trials | ||||||||
50 |
0 |
0 |
1 (3.8) |
36 |
1 year: 96
3 years: 74 |
1 year: 88
3 years: 68 |
1 year: 91.3
3 years: 74 | |
Case series | ||||||||
Alves (2009) [13] |
61 |
2 (3.3) |
0 |
0 |
35.9 |
3 years: 94 |
3 years: 78 |
n/a |
Parsa (2011) [16] |
51 |
0 |
0 |
0 |
27 |
5 years: 77.7 |
5 years:77.3 |
5 years: 98 |
Kang (2011) [17] |
76 |
4 (5) |
1 (1.3) |
0 |
34 |
1 year: 86
3 years: 80 |
1 year: 72
3 years: 59 |
1 year: 89
3 years: 86 |
Andacheh (2012) [18] |
73 |
10 (14) |
1 (1.3) |
1 (1.3) |
18 |
1 year: 81 |
1 year: 85 |
1 year: 86 |
Mani (2012) [19] |
58 |
3 (5.2) |
0 |
1 (1.7) |
n/a |
1 year: 89
3 years: 64 |
1 year: 85
3 years: 71 |
|
Cumulative |
369 |
5.6 % |
0.4 % |
1.1 % |
Table 2.3
Results for medical treatment in chronic uncomplicated Type B aortic dissection
Author, year (ref.#) |
n |
30 days mortality N (%) |
Early CVA N (%) |
Early SCI N (%) |
Mean f/up (m) |
Survival (%) |
Aortic event freedom rate | |
---|---|---|---|---|---|---|---|---|
Aorta related death, reintervention, expansion free (%) |
Aorta related death free (%) | |||||||
Prospective randomized controlled trials | ||||||||
68 |
0 |
0 |
0 |
69 |
1 year: 82.5
15 years: 80.7 years: 97 |
1 year: 82.5
5 years: 53.9 |
1 year: 97
5 years: 80.7 | |
Prospective nonrandomized trials | ||||||||
Jia (2013) [12] |
68 |
0 |
0 |
0 |
69 |
1 year: 97
5 years: 80.7 |
1 year: 82.5
5 years: 53.9 |
1 year: 97
5 years: 80.7 |
Cumulative |
163 |
0 |
0 |
0 |
Table 2.4
Results for TEVAR in chronic uncomplicated Type B aortic dissection
Author, year (ref.#) |
n |
30 days mortality N (%) |
Early CVA N (%) |
Early SCI N (%) |
Mean f/up (m) |
Survival (%) |
Aortic event freedom rate | |
---|---|---|---|---|---|---|---|---|
Aorta related death, reintervention, expansion free (%) |
Aorta related death free (%) | |||||||
Prospective randomized controlled trials | ||||||||
72 |
2 (2.8) |
1 (1.4) |
2 (2.9) |
69 |
1 year: 91.3
5 years: 91.3 |
1 year: 83.3
5 years: 73 |
1 year: 94.2
5 years: 93.1 | |
Prospective nonrandomized trials | ||||||||
Zipfel Restore registry (2011) [20] |
51 |
3 (5) |
0 |
2 (3.9) |
10 |
N/a |
n/a |
n/a |
Jia (2013) [12] |
208 |
0 |
0 |
2 (0.9) |
28.5 |
2 years: 87.5
4 years: 82.7 |
2 years: 87.8
4 years: 78.8 |
2 years: 91.6
4 years: 88.1 |
Case series | ||||||||
Kim (2009) [14] |
72 |
0 |
0 |
0 |
64.4 |
5 years: 92 |
5 years: 83.9 |
5 years: 98.3 |
Xu (2009) [15] |
84 |
1 (1.2) |
0 |
0 |
33.2 |
3 years: 91.7 |
5 years: 84.4 |
7 years: 75.2 |
Kim (2009) [14] |
72 |
0
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