Global Alliance for Cardiovascular Disease Prevention in Clinical Practice


Mortality and morbidity

Indicator

Premature mortality from noncommunicable disease

Target: A 25 % relative reduction in overall mortality from cardiovascular diseases, cancer, diabetes, or chronic respiratory diseases.

• Unconditional probability of dying between ages 30 and 70 from cardiovascular diseases, cancer, diabetes, or chronic respiratory diseases.












































Risk factors

Indicators

Behavioural risk factors

Harmful use of alcohol a

Target: At least a 10 % relative reduction in the harmful use of alcohol,b as appropriate, within the national context.

• Total (recorded and unrecorded) alcohol per capita (15+ years old) consumption within a calendar year in litres of pure alcohol, as appropriate, within the national context.

• Age-standardized prevalence of heavy episodic drinking among adolescents and adults, as appropriate, within the national context.

• Alcohol-related morbidity and mortality among adolescents and adults, as appropriate, within the national context.

Physical inactivity

Target: A 10 % relative reduction in prevalence of insufficient physical activity.

• Prevalence of insufficiently physically active adolescents defined as less than 60 min of moderate to vigorous intensity activity daily.

• Age-standardized prevalence of insufficiently physically active persons aged 18+ years (defined as less than 150 min of moderate-intensity activity per week, or equivalent).

Salt/sodium intake

Target: A 30 % relative reduction in mean population intake of salt/sodium.a

Age-standardized mean population intake of salt (sodium chloride) per day in grams in persons aged 18+ years.

Tobacco use

Target: A 30 % relative reduction in prevalence of current tobacco use in persons aged 15+ years.

• Prevalence of current tobacco use among adolescents.

• Age-standardized prevalence of current tobacco use among persons aged 18+ years.

Biological risk factors

Raised blood pressure

Target: A 25 % relative reduction in the prevalence of raised blood pressure or contain the prevalence of raised blood pressure according to national circumstances.

Age-standardized prevalence of raised blood pressure among persons aged 18+ years (defined as systolic blood pressure ≥140 mmHg and/or diastolic blood pressure ≥90 mmHg).

Diabetes and obesity b

Target: Halt the rise in diabetes and obesity.

• Age-standardized prevalence of raised blood glucose/diabetes among persons aged 18+ years (defined as fasting plasma glucose value ≥7.0 mmol/L (126 mg/dl) or on medication for raised blood glucose.

• Prevalence of overweight and obesity in adolescents (defined according to the WHO growth reference for school-aged children and adolescents, overweight—one standard deviation body mass index for age and sex and obese—two standard deviations body mass index for age and sex).

• Age-standardized prevalence of overweight and obesity in persons aged 18+ years (defined as body mass index ≥25 kg/m2 for overweight and body mass index ≥30 kg/m2 for obesity).




















National systems response

Indicator

Drug therapy to prevent heart attacks and strokes

Target: At least 50 % of eligible people receive drug therapy and counselling (including glycaemic control) to prevent heart attacks and strokes.

Proportion of eligible persons (defined as aged 40 years and over with a 10-year cardiovascular risk ≥30 %, including those with existing cardiovascular disease) receiving drug therapy and counselling (including glycaemic control) to prevent heart attacks and strokes.

Essential noncommunicable disease medicines and basic technologies to treat major noncommunicable diseases

Target: An 80 % availability of the affordable basic technologies and essential medicines, including generics, required to treat major noncommunicable diseases in both public and private facilities.

Availability and affordability of quality, safe and efficacious essential noncommunicable disease medicines, including generics, and basic technologies in both public and private facilities.

7].

The targets have a political dimension to all of them and there were important omissions. Diet is a major determinant of cardiovascular disease and fatty acid composition—saturated, monounsaturated and polyunsaturated—was not addressed. Nor were trans fatty acids which are widely used by the food industry in processed foods such as margarines. A substantial reduction in saturated fat consumption, and the elimination of trans fatty acids in all food production, could have a major impact on reducing the incidence of cardiovascular disease. Substitution of saturated fats in part with polyunsaturated fatty acids, both n-6 fatty acids which mainly come from plant foods and n-3 fatty acids coming mainly from fish oils, will further reduce cardiovascular disease. The current recommendations of professional bodies are to reduce saturated fat to <10 % of total energy intake and to substitute polyunsaturated fatty acids. Trans fatty acids should be eliminated from the human diet. The omission of fats from the lifestyle targets was political because it will impact directly on the business of major food manufacturers but this does not preclude national action. Several countries have already banned the use of trans fatty acids in all manufactured foods although this product continues to be widely used around the world. Other important aspects of the diet were also omitted from the targets. Sugars in the form of simple carbohydrates, widely used in sweetened soft drinks and other foods are a major source of calories in the diet and regular consumption is associated with the development of obesity and type 2 diabetes. Sweetened soft drinks have no nutritional value and therefore have no part in a healthy diet which should encompass a wide variety of wholegrain products, fresh fruit and vegetables. The combination of unhealthy eating and physical inactivity is driving the epidemic of obesity and, as a consequence, type 2 diabetes. To halt the rise in obesity and diabetes is not sufficient as a target because in some western populations a majority of the adult population are already overweight. To halt a further rise is important but this adverse trend needs to be reversed. This requires action at a population level on adopting healthy eating and becoming more physically active at the same time. To achieve the recommendation that all adults should spend 2.5–5.0 h a week on physical activity, or aerobic exercise training of at least moderate intensity, or 1–2.5 h per week on vigorous intense exercise, requires radical changes in the built environment in order to facilitate such activity in everyday life. Lifestyle also impacts directly on blood pressure, lipids and glucose and although there is a target for blood pressure, and one for diabetes, there is no target for cholesterol. Low density lipoprotein cholesterol (LDL-C) is a major risk factor for CVD, just like blood pressure and glucose, and high density lipoprotein cholesterol (HDL-C) is protective. The concentrations of both LDL-C and HDL-C are influenced by lifestyle, both diet and physical activity, and a target for LDL-C would also have been appropriate.

At the 66th World Health Assembly in May 2013 the WHO Global Action Plan for the Prevention and Control of Non-communicable Diseases 2013–2020 was endorsed [7] (Table 2). The vision is a world free of the avoidable burden of noncommunicable diseases.


Table 2
WHO global action plan for prevention and control of noncommunicable diseases
























Global action plan for the prevention and control of noncommunicable diseases 2013–2020

Overview

Vision: A world free of the avoidable burden of noncommunicable diseases.

Goal: To reduce the preventable and avoidable burden of morbidity, mortality and disability due to noncommunicable diseases by means of multisectoral collaboration and cooperation at national, regional and global levels, so that populations reach the highest attainable standards of health and productivity at every age and those diseases are no longer a barrier to well-being or socioeconomic development.

Overarching principles:

• Life-course approach

• Empowerment of people and communities

• Evidence-based strategies

• Universal health coverage

• Management of real, perceived or potential conflicts of interest

• Human rights approach

• Equity-based approach

• National action and international cooperation and solidarity

• Multisectoral action

Objectives

1. To raise the priority accorded to the prevention and control of noncommunicable diseases in global, regional and national agendas and internationally agreed development goals, through strengthened international cooperation and advocacy.

2. To strengthen national capacity, leadership, governance, multisectoral action and partnerships to accelerate country response for the prevention and control of noncommunicable diseases.

3. To reduce modifiable risk factors for noncommunicable diseases and underlying social determinants through creation of health-promoting environments.

4. To strengthen and orient health systems to address the prevention and control of noncommunicable diseases and the underlying social determinants through people-centred primary health care and universal health coverage.

5. To promote and support national capacity for high-quality research and development for the prevention and control of noncommunicable diseases.

6. To monitor the trends and determinants of noncommunicable diseases and evaluate progress in their prevention and control.

The goal is “To reduce the preventable and avoidable burden of morbidity, mortality and disability due to noncommunicable diseases by means of multisectoral collaboration and cooperation at national, regional and global levels, so that populations reach the highest attainable standards of health and productivity at every age and those diseases are no longer a barrier to wellbeing or socioeconomic development.”
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Jul 13, 2016 | Posted by in CARDIOLOGY | Comments Off on Global Alliance for Cardiovascular Disease Prevention in Clinical Practice

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