The interesting case report by Rojas-Marte et al. , published ahead of print in the Journal on July 31, 2014, about a 31 year-old woman who suffered Takotsubo syndrome (TTS), complicated by cardiac arrest and cardiogenic shock, following an overdose of ibuprofen and diphenhydramine, and was treated successfully with extracorporeal membrane oxygenation, provides me with the opportunity to bring to the attention of the authors a newly described association of TTS with early transient electrocardiogram (ECG) attenuation of the QRS complexes (ATTQRS) . Perusal of the 3 ECGs recorded upon admission, at ~ 1 hour, and at 36 hours later, reveals ATTQRS in the limb leads which are evident by comparison between the ECG #3 and ECGs, #1 and #2. Also transient ATTQRS with subsequent restoration of the amplitude of the QRS complexes was shown in the precordial leads (particularly V3 – V5), evident by comparisons of the 3 ECGs . These ATTQRS, which may have a role in the diagnosis of TTS, have been attributed to the ensuing myocardial edema, as detected by cardiac magnetic resonance imaging . I would be grateful to the authors if they could provide a comparison of the 3 ECGs, with a possibly available ECG prior to the inception of TTS, or subsequent ECGs recorded during hospitalization or at follow-up.