Background
Diabetes mellitus (DM) plays a major role in the development and progression of coronary artery disease and negatively impacts clinical outcome in patients undergoing revascularization. Drug-eluting stents (DES) significantly reduce restenosis when compared with bare metal stents. Even so, most of the series published show a less favorable clinical and angiographic outcome in diabetics. However, little is known about the outcome of diabetics undergoing percutaneous coronary intervention (PCI) to treat left main coronary artery (LMCA) disease. Thus, the aim of our study was to assess the influence of diabetes on short- and mid-term outcome of patients undergoing coronary angioplasty and stent implantation for left main disease.
Methods
A total of 334 consecutive patients from three tertiary hospitals who underwent PCI for de novo lesions in a left main coronary artery, 141 (42.3%) diabetic and 193 (57.7%) nondiabetic, were identified retrospectively and analyzed.