Background
Little is known about the association between obesity and bleeding complications after percutaneous coronary intervention (PCI). We investigated the impact of body mass index (BMI) on PCI-related bleeding and whether the use of bivalirudin that is known to reduce bleeding compared to heparin modifies this relationship.
Methods
From 2000 to 2009, 16,783 patients who underwent PCI were divided according to the BMI level: underweight (<18.5 kg/m 2 ), normal weight (18.5–24.9), overweight (25–29.9), Class I (30–34.9), Class II (35–39.9), and Class III obesity (≥40). Bivalirudin was used in 11,433 patients and heparin in 5350 for PCI. In-hospital transfusion and major bleeding (hematocrit drop ≥15% or gastrointestinal bleeding) were systematically collected.
Methods
From 2000 to 2009, 16,783 patients who underwent PCI were divided according to the BMI level: underweight (<18.5 kg/m 2 ), normal weight (18.5–24.9), overweight (25–29.9), Class I (30–34.9), Class II (35–39.9), and Class III obesity (≥40). Bivalirudin was used in 11,433 patients and heparin in 5350 for PCI. In-hospital transfusion and major bleeding (hematocrit drop ≥15% or gastrointestinal bleeding) were systematically collected.
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