Complications, risks, and consequences
Estimated frequency
Most significant/serious complications
Fever (mild, moderate, high)a
5–20 %
Myocardial problems (cardiac failure, infarction)a
1–5 %
Renal failurea
1–5 %
Jaundicea
1–5 %
Immunological cross priminga (immunization; cellular activation or tolerance induction)
1–5 %
Rare significant/serious problems
Infection (bacterial, fungal, viral, other)
Cellulitis
0.1–1 %
Systemic
<0.1 %
Disseminated intravascular coagulationa
<0.1 %
Incompatibility with other fluidsa
0.1–1 %
Intravascular hemolysisa
0.1–1 %
White blood cell incompatibilitya
0.1–1 %
Air embolisma
<0.1 %
Multisystem organ failurea
0.1–1 %
Deatha
<0.1 %
Less serious complications
Extravasation
0.1–1 %
Skin rash
5–20 %
Table 2.2
Noninfectious risks and complications of transfusion
Risk | Estimated frequency |
---|---|
Earlier complications: immediate to hours | |
Fever nonhemolytic, non-septic transfusion reaction | 0.1–1 % |
Volume circulatory overloada | 1–5 % |
Hemolysis | <0.1 % |
Transfusion acute pulmonary injury | < 0.1 % |
Allergic reaction – mild, moderate | 1–5 % |
Allergic reaction – severe anaphylaxis | <0.1 % |
Extravasation of transfusatea | 0.1–1 %
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