(1)
Pediatric Cardiology, Policlinico S.Orsola-Malpighi, Bologna, Italy
We did not start from the action potential, and we have deliberately not got bogged down in vectorcardiographic analysis. So we can say that Willem Einthoven is our notable absentee. The “child” vision requires an intuitive approach which nevertheless seeks to translate the deep, unconscious electrophysiology into a concept of surface: the vector and its symbol, the arrow shot by ions that travel across the membrane proteins.
The activity of the heart creates an electric field that can be detected by surface electrodes . This electrical activity may be assimilated to a dipole, a system consisting of two electric charges of equal and opposite sign and separated by a constant distance in time. When the atria (or ventricles) undergo depolarization, the wave that spreads across the muscle takes many different directions simultaneously and can be represented by arrows. Each arrow represents a different individual vector, and the set of these individual vectors can be summarized by the mean (or resulting) electrical vector. It is best to keep in mind that the forces generated in opposite directions can neutralize each other. The most intuitive way to read the ECG is to think of this vector (which applies to every wave from P to T) as an arrow that we see from our vantage points and that is the standard 12-lead ECG. The direction of this arrow relative to the electrode determines the magnitude of the recorded voltage (the voltage of course also depends on the mass of the cardiac tissue involved). When the arrow is approaching, the electrode which sees the tip will record a positive voltage and then a positive wave; conversely, when the arrow moves away from the electrode and this sees the bottom, it will react with a negative voltage and a negative wave (Fig. 2.1).
Fig. 2.1
The Riace Bronzes as models for a 12-lead ECG in a 12-year-old boy. Bronze (a) the one with the more restless style. Frontal plane, standard limb leads (I, II, III), and augmented unipolar (aVR, aVL, aVF); like the style of the statue, these leads are sensitive to movements and artifacts. Bronze (b) horizontal plane, precordial leads V1 (fourth intercostal space, right parasternal), V2 (fourth intercostal space left parasternal), V3 (equidistant between V2 and V4), V4 (fifth intercostal space midclavicular line), V5 (fifth intercostal space anterior axillary), V6 (fifth intercostal space, axillary media); like the style of the statue, these leads are more stable and relaxed.
The arrow that we imagine on the ECG goes a long way and travels across a sky called conduction system . This skyway begins in the pale cells of the sinoatrial node , located in the upper right atrium where the superior vena cava ends. Hence, the impulse that arises from spontaneous depolarization regulated by the autonomic nervous system and by circulating hormones will go toward the left atrium through the muscle cells but also past the Bachman bundle and toward the ventricles with internodal pathways and through the working myocardium. The AV junction consists of a proximal part, the AV node, and a distal part, the bundle of His. From the His bundle, the two main branches will finally start and will end in the ventricles to the Purkinje fibers. Now ventricles are activated and the electromechanical coupling can move the blood. The main ventricular vector can be divided in three parts, taking into account that the right ventricle starts to depolarize shortly after the left ventricle: the first part represents the resultant force of the septum (vector 1), moving from the left toward the right and triggering the q wave in V6 (and lead I and aVL); the second represents the activation of the free wall of ventricles (vector 2); the third represents the activation of the postero-basal aspects of ventricles (vector 3).
2.1 Technical Aspects
Before moving on to atrium and ventricular dissection, it is worth remembering some technical aspects. You should always check that paper speed and calibration are standard and thus respectively 25 mm/s and 10 mm = 1 mV. An increase in speed or amplitude may be required when greater precision in estimation of intervals or small amplitude waves is important. True dextrocardia must be distinguished from misplacement of the limb leads (the so-called nurse’s dextrocardia).
When faced with an improbable ECG, you have to question the correctness of lead placement, sometimes poorly positioned due to staff carelessness, thoracic deformity, dressings, etc. [1, 2] The surface ECG is a simple technique, but that does not mean it can be performed superficially. Just like cooking, it is the simplest recipes that require perfection of the few necessary ingredients. Every laboratory should comply with the standard placement of the electrodes, and nurses should be skilled in being able to put children of all ages at their ease, resorting to various arts ranging from soap bubbles to smartphones.
In remote-viewed tracings, whether sent by fax or other means, you have to make sure that the relationship with the original is 1:1; even small differences of scale can lead to blunders, for example in the calculation of the QT interval (if you don’t know the scale, you can count the little boxes that at standard paper speed correspond to 40 ms). Sometimes there are funny artifacts: the oscillatory ventilation often used in neonatal intensive care can simulate drug-resistant flutter (diagnosis and therapy are electric, just switch off the oscillator) [3]. Even hiccups can create bizarre waves resembling extrasystoles which are neither supraventricular nor ventricular, but simply underventricular or diaphragmatic. Congenital heart disease may require nonstandard leads such as V3R, V4R, and V7: the first two increase the sensitivity of the right overload [4], while V4R (positioned on the right midclavicular fifth intercostal space) can be an excellent alternative to V1–V2 which cannot be applied due to dressings or for other reasons. With ECGs that are “RBBB like” or with an “atypical” RBBB, in family members of patients with Brugada syndrome , or in the case of unexplained syncope, in addition to the ECG standard you should do an ECG with right precordial leads (V1 and V2) moved high in the third and in the second intercostal space. In the same conditions, it is also useful to perform an ECG in the course of fever as it is known that hyperthermia can unmask the Brugada pattern. Modern electrocardiographs have sample rate and bandwidth higher, respectively, than 500 samples/s and 250 Hz – they write very well but they don’t read quite so well. Automatic diagnosis may be incomplete, petulant, or catastrophic and is not always reliable, especially when the machines do not know they are dealing with a child and see infarction instead of infants [5]. “Manual” diagnosis should avoid as much as possible scary terms like “block,” “delayed,” “nonspecific alteration,” and “anomaly” which are not much help. When these terms are unavoidable, they should be followed by conclusions that are as reassuring as possible. You should also avoid defensive adverbs and phrases such as likely and cannot be excluded followed by a dozen differential diagnoses. The perfect report consists of a single word: “N o r m a l.” A broken clock tells the correct time at least twice a day. Cardiologists who are too far forward or too far back never get it right. For all the time and amplitude parameters, refer to the normal value tables; the Davignon and Rijnbeek tables are still useful [6, 7] (Table 2.1).
Table 2.1
Values of normal ECG parameters according to age