19
Aortic Diseases
A 50-year-old male with a history of a heart murmur for most of his adult life sees you in the clinic with symptoms of dyspnea on minimal effort and chest pain with minimal effort. Blood pressure (BP) is 130/80 mmHg, heart rate is 72 bpm. Grade III/VI harsh systolic ejection murmur is heard in the right upper sternal border. Echocardiogram showed a bicuspid valve with aortic valve area of 0.6 cm2. What is the lifetime risk of aortic dissection in this patient?
- 2–4%
- 4–6%
- 6–7%
- 10–12%
- 2–4%
Aortopathy associated with bicuspid aortic valve is due to which of the following?
- Abnormal fibrillin
- Vascular smooth muscle cell apoptosis
- Matrix metallopeptidase 9
- All of the above
- A and C only
- Abnormal fibrillin
The right/left fusion pathology in a bicuspid valve is seen commonly. What is its incidence?
- 20%
- 40%
- 60%
- 80%
- 20%
The sites of aortic dissection may be (a) just past the left subclavian artery, (b) 3 cm distal to the aortic valve, and (c) at the aortic arch. Which of the following options matches the aortic dissection sites in decreasing order?
- a, b, c
- b, c, a
- b, a, c
- a, c, b
- a, b, c
The treatment of choice in a 49-year-old male with acute type III aortic dissection, minimally dialted aorta with no leak, good flow in false lumen, BP of 200/100 mmHg, severe interscapular pain, pallor, and tachycardia is which of the following?
- Emergency surgery
- Endovascular graft implantation with fenestration
- Intravenous (IV) nitroprusside
- IV esmolol
- Emergency surgery
A 70-year-old patient with a history of three-drug hypertension and tobacco use presents to the emergency room with acute onset of substernal chest pain and electrocardiogram showing St elevation in inferior leads. His BP is 80 mmHg systolic in the left arm and 150 mmHg systolic in right arm. What is your test of choice?
- Emergency coronary angiography
- Echocardiography
- Computed tomography (CT) of the chest without contrast
- CT of the chest with contrast
- Emergency coronary angiography
The angiogram in Figure 19.7 is most likely to be associated with which of the following?
- 70-year-old African American woman
- 38-year-old Asian Indian woman
- 35-year-old Polish male
- 60-year-old Peruvian male
- 70-year-old African American woman
An 80-year-old woman presents with 20 lb weight loss over the last 6 months. She also reports nausea and diarrhea and states she has to eat small meals as she has abdominal pain if she eats normal portions. She has a history of coronary artery bypass grafting, done 10 years ago. She had traveled to India 6 months ago. What is the test that will have the highest yield?
- Esophagogastroduodenoscopy
- Colonoscopy
- Infectious disease consultation
- CT with contrast of the chest and abdomen
- None of the above
- Esophagogastroduodenoscopy
The patient in Figure 19.9 has history hypertension and shortness of breath. Which of the following does the patient have?
- Hyperparathyroidism
- Lymphoma
- Prostate cancer
- None of the above
- Hyperparathyroidism
A patient presents with “trash foot” after a cardiac catheterization with the TEE image shown in Figure 19.10. There is a palpable pulse and the foot is warm. Which of the following would you order?
- IV prostaglandin
- IV steroids
- IV heparin
- IV nitroglycerine
- None of the above
- IV prostaglandin
What is your test of choice to make the diagnosis of the patient in Question 19.10?
- Arterial duplex of the lower extremities
- Venous duplex study of the lower extrenities
- CT of the abdomen
- Abdominal ultrasound
- Arterial duplex of the lower extremities
A 53-year-old male presents with symptoms of progressive hoarseness. Figure 19.12 shows the TEE (long-axis view) done. What is the best next step?
- IV vancomycin and gentamicin
- Repeat echocardiography in 2 weeks
- Esmolol drip
- CT of the chest with contrast
- IV vancomycin and gentamicin
A 58-year-old male is known to have Marfan syndrome. His echocardiogram shows ascending an aortic aneurysm 4.1 cm in size. What is the next step?
- CT every 6 months
- Echocardiogram every 6 months
- Annual CT or magnetic resonance imaging (MRI)
- Echocardiogram every 3 months
- CT every 6 months
A 43-year-old male had recent surgery for a dissecting aortic aneurysm. Which of the following is/are recommended?
- CT or echocardiogram at 6 and 12 months after surgery
- Lifelong beta blockade
- Use of homografts to replace infected prostheses is contraindicated
- Control BP to less than 135/80 mmHg
- B and D
- A and D
- CT or echocardiogram at 6 and 12 months after surgery
A 60-year-old male was diagnosed with infrarenal abdominal aortic aneurysm (AAA) of 5.5 cm. What should this patient have?
- CT every 6–12 months
- Should undergo repair
- Monitored by ultrasound every 3–6 months
- Only A and C
- CT every 6–12 months
Endovascular repair of the aneurysm of the descending thoracic aorta is associated with which of the following complications compared with open surgical repair?
- Higher risk of paraplegia with endovascular repair
- Lower risk of paraplegia with surgical repair
- Higher risk of respiratory failure with open repair
- Higher risk of respiratory failure with endovascular repair
- Higher risk of paraplegia with endovascular repair
A 50-year-old woman presents to your office with 6-month history of hypertension that has been difficult to control, headaches, fatigue of the lower extremities on minimal effort, and claudication if she pushes herself. She has had malaise, low-grade fevers, and night sweats. Her BP is 200/105 mmHg in both upper extremities and 100/60 mmHg in both of her ankles. What is the diagnosis?
- Takatsubo’s syndrome
- Coarctation of the aorta.
- Mid aortic syndrome
- Bilateral iliac artery stenosis
- Takatsubo’s syndrome
With which of the following is 45,X chromosomal anomaly associated?
- Development of complete heart block
- Ventricular septal defect
- Aortic aneurysm and dissections
- Tall stature and a violent personality
- Development of complete heart block
“Bamboo” spine is associated with which of the following?
- Ascending aortic aneurysm
- Uveitis
- Arthritis
- Ulcerative colitis
- A, B, and C
- A, C, and D
- All of the above
- Ascending aortic aneurysm
Leriche syndrome is associated with which of the following?
- Impotence
- Buttock claudication
- Atrophy of the lower extremities
- All of the above
- A and B only
- Impotence
Which of the following describes collateral arterial pathways around total occlusions of the infrarenal aorta?
- Inferior epigastric artery to the internal mammary artery
- Lumbar artery to the hypogastric artery
- Inferior mesenteric artery to the hypogastric artery
- The sacral artery to the hypogastric artery
- A and B only
- All of the above
- A, B, and C only
- Inferior epigastric artery to the internal mammary artery
A 68-year-old woman presents with severe anterior unrelenting chest pain that radiates to her back. BP is 200/110 mmHg. She has a CT scan of the chest, shown in Figure 19.22a. Which of the following is the next best step?
- Coronary angiography and aortogram
- TEE
- Cardiothoracic surgery consultation and proceed to the operating room
- MRI of the chest
- Coronary angiography and aortogram
Which of the following is the treatment of choice in the 80-year-old patient in Figure 19.23a with advanced chronic obstructive pulmonary disease and hypertension? She is status post mastectomy 3 years ago with no residual disease.
- Endovascular repair
- Open surgical repair
- Risk factor modification with conservative therapy
- Endovascular repair
You successfully repaired a 6.5 cm infrarenal aortic aneurysm a year ago. The aneurysm has continued to grow by 1 cm on a follow-up CT scan. There is no contrast seen within the sac of the aneurysm. What is this an example of?
- Type I endoleak
- Type II endoleak
- Type III endoleak
- Type IV endoleak
- Type V endoleak
- Type I endoleak
True or false, “sartans” slow the growth of aneurysms in Marfan syndrome?
- True
- False
- True
Which of the following may 45,X0 be associated with?
- Brachiofemoral delay
- Bicuspid aortic valve
- Dilatation of the aorta
- Impaired glucose tolerance
- All of the above
- Brachiofemoral delay
A bifid uvula is seen in which of the following?
- Ehlers–Danlos syndrome (EDS)
- Loeys–Dietz syndrome (LDS)
- Aneurysms–osteoarthritis syndrome (AOS)
- Arterial tortuosity syndrome (ATS)
- Marfan syndrome
- Ehlers–Danlos syndrome (EDS)
The non-syndromic forms of thoracic aortic aneurysm and dissection (nsTAAD) may be associated with bicuspid aortic valve and/or persistent ductus arteriosus and display typical cystic medial necrosis on pathological examination. Mutations in genes (FBN1, TGFBR1, and TGFBR2) are frequently seen.
- True
- False
- True
The most characteristic and frequently reported clinical presentation of an intimal angiosarcoma of the aorta is the embolic occlusion of the mesenteric or peripheral artery. Leiosarcomas and fibrosarcomas originate from the media or adventitia of the aortic wall. Which rare tumor of the aorta is most common?
- Angiosarcoma
- Leiosarcoma
- Fibrosarcoma
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- Angiosarcoma